[Current status of migraine chronification in Japan].
نویسنده
چکیده
Chronification of migraine headache is one of the major issues to resolve urgently. The prevalence of chronic migraine is close to 2%, and the chronification occurs in approximately 2.5% of episodic cases annually.The pathophysiology of transformation from episodic to chronic migraine is still unclear. It is considered that there are several risk factors for migraine chronification; 1) non-modifiable: age, low education/socioeconomic status, and head injury, 2) modifiable: attack frequency, obesity, medication overuse, stressful life events, caffeine overuse, snoring, and other pain syndrome, 3) currently putative: allodynia, proinflammatory states, prothrombotic states, and specific genes.There were a few clinical reports concerning to the migraine transformation from abroad, but few data from Japan. The prevalence of chronic daily headache in our headache clinic in Japan was 20-30%. The medication overuse headache was the most prevalent form in the highest attack frequency (>15 days/month) grope. Discontinuation of overused medication and administration of prophylactic medication were effective, and 40% of followed cases kept out of MOH at two years later.
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ورودعنوان ژورنال:
- Rinsho shinkeigaku = Clinical neurology
دوره 23 11 شماره
صفحات -
تاریخ انتشار 2013